The Finnish Cultural Foundation has granted 32 500 € for the design, synthesis and evaluation of boron containing amino acids for treatment of malignant brain tumors. The study aims to development of novel amino acid-based boron carriers to be used in boron neutron capture therapy (BNCT) of malignant brain tumors.
The BNCT is a method based on a biologically targeted boron carriers and their activation by neutrons. The capture of neutrons by boron leads into release of a short-range radioactivity which will lead to death of cancer cells. However, the short range of the radiation will result in spared normal tissue.