Welcome to our team Anna!

Anna Olkkonen, a BSc from the School of biomedicine (University of Eastern Finland) started recently her MSc thesis in our research group. Her thesis focuses in the computational study of TRPA1 attenuators. During the summer, she will build model of TRPA1 ion channel, study the different binding sites and predict the different binding modes for...

New Details of Coumarin Metabolism

Just published results revealed details on species differences on Couamrin metabolis. Researchers from several collaborating research groups showed that substituted 7-hydroxycoumarins undergo sulfonation metabolism in different rates in different animal species. Also, the substitution of coumarins affected the rate of metabolism. Results give important knowledge on metabolism in mammalians that can be used to understand...

New Research on Coumarin Metabolism Just Published!

Recently, an article by Professor Risto Juvonen in collaboration with Medicinal Organic Synthesis Research Group was published in Planta medica. Most intereting results were differences in metabolism of coumarins between species. The full text article can be read at: https://www.researchgate.net/publication/330976257_Metabolism_of_Scoparone_in_Experimental_Animals_and_Humans

New Light Shed to Anti-Inflammatory Effect of Psoralens

A research published in Heterocyclic chemistry shed new light on the anti-inflammatory effects of substituted psoralen derivatives. Dr Timonen showed in collaboration with the Immunopharmacology Research group from the School of Medicine, University of Tampere that psoralens, a certain group of furocoumarins, exhibits anti-inflammatory properties against NO production and iNOS expression. In the study, it...

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